Lugar / Place: Universidad Austral de Chile
Dirección / Address : Aula Magna, Campus Isla Teja, Valdivia, Chile.
Fecha / Date: 02 al 05 diciembre de 2025
Conferencias / Lectures
*Title: “Dra. Katia Gysling: una vida dedicada a la neurofarmacología y a la formación de personas”, Opening Conference.
Speaker: Dr. María Estela Andrés, Pontificia Universidad Católica de Chile, Chile.
*Title: “Pentameric ligand-gated ion channels: Bridging molecular insights and clinical promise”
Speaker: Dr. Cecilia Bouzat, Universidad Nacional del Sur, Argentina.
*Title: “Mapping GLP-1R Signaling in Human POMC Neurons: A Central Mechanism of Anti-obesity Drug Action”
Speaker: Dr. Simone Mazzaferro, University of Cambridge, United Kingdom.
*Title: “The therapeutic potential and molecular signature of cannabidiol in depression”
Speaker: Dr. Samia Joca, Aarhus University, Denmark
*Title: «From Occupation Theory to Biased signaling, 100 years of Pharmacology Thinking and Experimentation», Closing Conference, Dr. Luis Núñez.
Speaker: Dr. Juan Pablo García-Huidobro, Universidad de Santiago de Chile, Chile.
Simposios / Symposia
Symposium Neuro-Gastropharmacology: “Innovating in pharmacology: neuroimmune, aging, natural compounds for neuroprotection, and intestinal microbiota-based therapies”. Chair: Dr. Javier Bravo
“Targeting the gut microbiota-immune-brain axis as a therapeutic approach in Parkinson’s disease”. Dr. Rodrigo Pacheco, Fundación Ciencia y Vida, Universidad San Sebastián, Chile.
“Bioactive Molecules and Brain Health: Unlocking Neuroprotection through Natural Products”, Dra. Alejandra Arancibia, Pontificia Universidad Católica de Valparaíso, Chile.
“Microbial-based strategies to promote healthy aging”, Dr. Erick Riquelme, Pontificia Universidad Católica de Chile, Chile.
“Targeting the gut microbiota to treat neuropsychiatric disorders”, Dr. Javier A. Bravo, Pontificia Universidad Católica de Valparaíso, Chile.
Symposium Cancer Pharmacology: “Novel targets in cancer pharmacology: basic, clinical, and technological approaches” Chair: Dr. Rodrigo Castillo
“Cardiovascular risk in a cohort of childhood cancer survivors: pilot study of exercise training and SGLT2 inhibitors in cardiometabolic markers”. Dr. Rodrigo Castillo, Universidad de Chile, Chile.
“Transactivation between P2Y2 and HER2 receptors and its potential role in gastric cancer”. Dr. Claudio Coddou Álvarez, Universidad Católica del Norte, Chile.
“From Gene to Cure: Recombinant L-Asparaginase Production for Leukemia Therapy”. Dr. Jorge Farías Avendaño, Universidad de la Frontera, Chile.
Symposium Chronic metabolic disorders: “Experimental models for studying mitochondrial metabolism in long-term diseases”. Chair: Dr. Mario Herrera-Marschitz
“Introductory remarks: Targeting Mitochondrial Complex I to rescue from metabolic deficits induced by perinatal asphyxia”. Dr. Mario Herrera-Marschitz, Universidad de Chile, Chile.
“SeaHorse technology for monitoring mitochondrial function”. Dr. Felix Urra, Universidad de Chile, Chile.
“Mitochondria in Human Brain Organoids: the challenging”. Dr. Jose Inzunza, KI-University Hospital Huddinge, Sweden.
“Neurodegenerative disorders: Novel pharmacological opportunities”. Dr. Nibaldo Inestrosa, Universidad de Magallanes, Chile.
Symposium Neuropharmacology and metabolic disorders: “Obesity: Emerging Pathophysiological Mechanisms and Novel Therapeutic Opportunities” Chair: Dr. Ramón Sotomayor-Zárate y Dra. Andrea Del Campo
“Molecular effects of obesogenic diets in POMC neurons: Can weight loss reverse obesity-induced effects? Dr. Estefanía Tarifeño, Universidad de Concepción, Chile.
“Time-Restricted Feeding as a Potential Treatment for Sarcopenic Obesity”. Dr. Andrea Del Campo, Pontificia Universidad Católica de Chile, Chile.
“Maternal High-Fat Diet Exposure Impairs Offspring hippocampal synaptic transmission and cognitive function”. Dr. Marco Fuenzalida, Universidad de Valparaíso, Chile.
“Role of the Hippocampus–Lateral Septum–Lateral Hypothalamus Pathway in the Regulation of Food Intake and the Development of Obesity”. Dr. Ramón Sotomayor, Universidad de Valparaíso.
Symposium Drug Delivery: “Bridging the Gap: Advanced In Vitro, Ex Vivo, and In Vivo Models for Characterizing and Predicting the Performance of Drug Delivery Systems”. Chair: Dr. Javier Morales
“Integrating In Vitro, Ex Vivo, and Disease-Specific In Vivo Models for the Development of Novel Drug Delivery Systems”. Dr. Javier Morales, Universidad de Chile, Chile.
“Microphysiological Systems on a Chip: Novel Platforms for Evaluating Nanomedicine Efficacy and Toxicity in Drug Delivery”. Dr. Natalia Hassan, Universidad Tecnológica Metropolitana, Chile.
“Development and characterization of dry powder formulations for nose-to-brain delivery. Use of in vitro setups modified USP cascade impactors, and 3D-printed nasal replica casts for deposition and permeation studies”. Dr. Daniel Moraga, Universidad de Valparaíso, Chile.
Symposium Immunometabolism: “Immunometabolic Modulation: Emerging Pathways for Therapeutic Development” Chair: Dr. Rafael Burgos
“Compounds of natural origin that play a therapeutic role in dogs (Canis lupus familiaris)». Dra. Alejandra Hidalgo, Universidad Austral de Chile, Chile.
“β-hydroxybutyrate disrupts neutrophil bioenergetics during TLR2/1 challenge: immunometabolic consequences of subclinical and clinical ketosisin dairy cattle”. Dr. John Quiroga, Universidad Austral de Chile, Chile.
“Obesity-Associated Metabolomic and Functional Reprogramming in Neutrophils from Horses with Asthma”. Dr. Gabriel Morán, Universidad Austral de Chile, Chile.
“Mitochondrial dysfunction in neutrophils under inflammatory conditions induced by D-lactate: immunometabolic consequences andtherapeutic perspectives”. Dr. Rafael A Burgos, Universidad Austral de Chile, Chile.
Symposium Medicinal Chemistry and Drug Design: “Innovative Drug Discovery Strategies for Neurodegenerative Diseases” Chair: Dr. David Ramírez
“A mixed ligand and target virtual screening for the discovery of brain permeables SGK1 inhibitors as protective agents for neurodegenerative and cardiovascular diseases”. Dra. Ana Martínez Gil, Centro De Investigaciones Biológicas, España.
“Constructing Neuroprotective Agents: Synthetic Strategies for Heterocyclic Chalcones and Derivatives”. Dr. Claudio Jiménez, Universidad de Concepción, Chile.
“From bytes to bench: AI-driven multitarget drug design for Alzheimer’s disease”. Dr. David Ramírez, Universidad de Concepción, Chile.
FINANCIAL SUPPORT
SPONSORS
