SOFARCHI – 2026 LECTURES AND SYMPOSIA

Conferencias / Lectures

Opening Conference:

*Title: “GABA pathway important for natural and nicotine rewards”

Speaker: Dr. Marina Picciotto, Yale School of Medicine, United States.

*Title: “The Age of Dinosaurs: A Window from Chile”

Speaker: Dr. Alexander Vargas Milne, Universidad de Chile, Chile.

*Title: “Brain heteroreceptor complexes in Parkinson’s disease: from molecular mechanisms to novel pharmacological strategies”

Speaker: Dr. Dasiel Óscar Borroto Escuela, IBIMA, Universidad de Málaga, España.

*Title: «GABAB receptors and kisspeptin: from metabolic regulation to pancreatic ductal adenocarcinoma»

Speaker: Dra. Noelia Paula Di Giorgio, Universidad Nacional de Quilmes, Buenos Aires, Argentina.

*Title: «Crossroads between cancer and regenerative medicine«

Closing Conference, Dr. Luis Núñez

Speaker: Caroline Weinstein Oppenheimer, Universidad de Valparaíso, Chile.

Simposios / Symposia

Symposium Neuropharmacology: “Classical and emerging therapeutics targeting central and peripheral neuronal receptors and channels: insights from molecular, functional and behavioral assays” Chair: Dr. Gonzalo Yévenes

“Recent Progress in Glycinergic Allosteric Modulators: From Ligand Binding to Functional Modulation and Analgesia”. Dr. Gonzalo Yévenes, Universidad de Concepción, Chile.

“Using novel activators of brake potassium channels as a pharmacological tool to tackle neuropathic pain”. Dr. Rodolfo Madrid, Universidad de Santiago de Chile, Chile.

“Modulating Striatal Glycine Receptors for Neuroprotection in Parkinson’s Disease”. Dr. Braulio Muñoz, University of Indiana, United States.

“Targeting the Vasopressinergic System in Amphetamine Use Disorder: Neurochemical and Behavioral Outcomes”. Dr. Georgina M. Renard, Universidad de Santiago de Chile, Chile.

Symposium Biopharmaceutical: “Pharmacological and Bioengineering Frontiers in Regenerative Medicine” Chair: Dr. Jorge Farias

“From laboratory to market: business models, scaling and commercialization of advanced and personalized therapies”. MBA Rodrigo Arancibia, CEO Grupo Cellus, Chile.

“Bioengineering platforms for the production of 3D cellular constructs: new models for the evaluation of biopharmaceuticals”. Dr. Mauricio Zamorano, Universidad de la Frontera, Chile.

“Biotechnological aspects in the production of biopharmaceuticals: processes, platforms and production challenges”, Dr. Jorge Farias Avendaño, Universidad de la Frontera, Chile.

Symposium Molecular Pharmacology and Medicinal Chemistry: “Ion Channels: Integrating Biophysics, Pharmacology and Bioinformatics in Translational Biomedicine” Chair: Dr. Gustavo Moraga-Cid

“Ion fluxes and fertility: Shaping fertilization through ion channel modulation”. Dr. Ingrid Carvacho, Universidad Católica del Maule, Chile.

“Targeting the TMC1 channel-scramblase duality: Computer-aided drug design as novel strategy for mechanistic otoprotection”. Dr. David Ramírez, Universidad de Concepción, Chile.

“Use of automated patch clamp in cardiac safety assessment: past, present and future perspectives”. Dr. Pietro Scaduto, Sophion Bioscience Inc. Arlington. Massachusetts, United States.

“Targeting Inhibitory Neurotransmission: New Allosteric Modulation Insights into Glycine and GABA-A Receptors”. Dr. Gustavo Moraga-Cid, Universidad de Concepción.

Symposium Sociedad Española de Farmacología: “New therapeutic strategies in cardiovascular diseases” Chair: Dr. Guillermo Diaz

“Non-lipid-lowering actions of PCSK9 inhibitors in atherosclerotic disease”. Dr. Oscar Lorenzo, Facultad de Medicina, Universidad Autónoma de Madrid, Spain.

“Novel Senotherapeutic Targets in Vascular Inflammaging”. Dr. Concepción Peiró Vallejo, Facultad de Medicina, Universidad Autónoma de Madrid, Spain.

“SGLT2 inhibitors reduce human vascular inflammation by interfering with cell glucose uptake”. Dr. Carlos Sánchez Ferrer, Facultad de Medicina, Universidad Autónoma de Madrid, Spain.

Symposium Ethnopharmacology: “The pharmacological actions of natural products” Chair: Dr. Alfredo Molina Berrios

“From the Chilean highlands to the laboratory: Lampayo’s chemistry and its pharmacological potential against prostate cancer». Dr. Waleska Vera Quezada, Universidad de Valparaíso, Chile.

“Interdisciplinary development of essential oil-based antibiofilm agents against Candida albicans”. Dr. Alfredo Molina Berrios, Universidad de Chile, Chile.

“Pharmacological validation of the traditional uses of Fuchsia magellanica Lam.: From chemical characterization to biological activity” Dr. Gabriela Valenzuela , Universidad de Chile, Chile.

“From Chilean Native Plants to Topical Formulations: Bioactive Prototype Development for the Management of Canine Pyoderma”. Dr. Jessica Bravo, Universidad Diego Portales, Chile.

Symposium Chemotherapy: “Rethinking cancer therapy: metabolic vulnerabilities, molecular targets, and drug repurposing across tumor types” Chair: Dr. Rodrigo López

“Exploiting metabolic vulnerabilities in KRAS-mutant lung cancer: polyamine and mevalonate pathway inhibition to potentiate KRAS inhibitors”. Dr. Rodrigo López, U. Austral de Chile, Chile.

“Targeting mitochondria in oral cancer: drug repurposing and VDAC/autophagy modulation as a synergistic antitumor strategy”. Dr. José Antonio Jara, Universidad de Chile, Chile.

“A synthetic SPINK7 peptide targeting HER2/neu: a novel therapeutic strategy against cisplatin-resistant oral squamous cell carcinoma”. Dr. Flavia Bruna, Universidad Nacional de Cuyo, Argentina.

Symposium Cardiovascular and Metabolic Pharmacology: “New drugs and mechanisms for cardiac and metabolic disease treatment” Chair: Dr. Raúl Vivar Sánchez

“Design of Mitochondria-Targeted Bioactive Molecules: A Medicinal Chemistry Strategy”. Dr. Cristián Suárez Rozas, Universidad Bernardo O’Higgins, Chile.

“Tracking Bioactive Metabolites: In Vivo Evaluation of Calafate and its Derivative henylacetic Acid on Adaptive Thermogenesis and Obesity”. Dr. Diego García Díaz, Universidad de Chile, Chile.

“Browning of white adipocytes induced by a mitochondria-targeted lipophilic cation derived from gallic acid”. Dr. Mabel Catalán Díaz, Universidad de Chile, Chile.

“New targets for the development of drug treatments against obesity-induced cardiac fibrosis”. Dr. Raúl Vivar Sánchez. Universidad de Chile, Chile.

Symposium Clinical Pharmacology: “Concepts of Clinical Pharmacy”” Chair: Dr. Rodrigo Castillo

“Optimizing vancomycin use: from therapeutic monitoring to clinical implementation”. Q.F. Camila Figueroa, Universidad de la Frontera, Chile.

“Drug Physicochemical Properties and Vascular Access Selection in Critically Ill Patients”. Q.F. Msci. Francisco Álvarez, Universidad Andrés Bello, Chile.

«From the science of medicine to clinical practice: the development of Clinical Pharmacy and local experience in Chile». Q.F. Felipe Quezada, Hospital San Borja Arriaran, Universidad Andrés Bello, Chile

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